儚む

はかなむ【儚む】

despair 《of the world》; lose all hopes 《of life》; despond 《of the future》; become pessimistic.

●世をはかなむ grow weary [sick] of the world; be tired of life

・世をはかなんで自殺する kill oneself [commit suicide] in despair [out of sheer pessimism]

・世を厭(_いと)い, 身をはかなむ be disgusted with the world and all it contains.